Decreased Immunologic Activity [PE] — Common Side Effects

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Side Effect	Total Reports	Drugs	Deaths	Hosp.	Life-Threat.
Death	5,476	2	5,448	466	33
Malignant neoplasm progression	3,842	2	1,145	1,082	143
Diarrhoea	3,432	2	397	1,478	156
Off label use	3,245	2	425	927	202
Fatigue	3,158	2	364	1,065	89
Stomatitis	2,873	2	216	675	81
Drug ineffective	2,842	2	399	659	287
Nausea	2,308	2	251	990	96
Dyspnoea	2,130	2	466	1,206	155
Product use in unapproved indication	2,042	2	324	505	107
Pyrexia	2,034	2	285	1,316	192
Pneumonia	1,966	2	407	1,161	306
Vomiting	1,738	2	248	962	103
Malaise	1,733	2	243	749	102
Decreased appetite	1,722	2	240	732	65
Rash	1,718	2	136	343	40
Weight decreased	1,678	2	252	729	97
Pain	1,617	2	217	636	180
Cough	1,613	2	229	738	86
Asthenia	1,550	2	302	775	81
Disease progression	1,462	2	257	181	21
Headache	1,275	2	100	441	50
Anaemia	1,228	2	273	670	128
Metastases to liver	1,047	2	232	257	46
Abdominal pain	979	2	171	622	79
Pneumonitis	966	2	155	412	58
Transplant rejection	946	2	64	220	154
Acute kidney injury	943	2	203	684	184
Product use issue	933	2	131	243	88
Hypertension	930	2	101	427	53