HIV Protease Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Foetal exposure during pregnancy | 4,232 | 7 | 549 | 469 | 122 |
| Maternal exposure during pregnancy | 2,147 | 7 | 45 | 221 | 34 |
| Drug interaction | 1,763 | 6 | 207 | 516 | 60 |
| Exposure during pregnancy | 1,723 | 7 | 32 | 213 | 13 |
| Virologic failure | 1,345 | 7 | 36 | 112 | 5 |
| Drug resistance | 1,109 | 7 | 222 | 122 | 2 |
| Premature baby | 1,101 | 7 | 118 | 187 | 79 |
| Abortion spontaneous | 988 | 5 | 38 | 64 | 2 |
| Death | 975 | 6 | 967 | 67 | 32 |
| Nausea | 898 | 7 | 18 | 491 | 20 |
| Depression | 831 | 6 | 175 | 209 | 10 |
| Off label use | 814 | 6 | 91 | 361 | 15 |
| Diarrhoea | 761 | 6 | 34 | 303 | 35 |
| Viral mutation identified | 754 | 7 | 8 | 28 | 0 |
| Lipodystrophy acquired | 741 | 7 | 1 | 76 | 36 |
| Pathogen resistance | 713 | 7 | 0 | 73 | 2 |
| Treatment failure | 690 | 7 | 235 | 26 | 1 |
| Treatment noncompliance | 681 | 6 | 34 | 117 | 6 |
| Vomiting | 680 | 7 | 21 | 421 | 12 |
| Premature delivery | 670 | 5 | 3 | 92 | 16 |
| Acute kidney injury | 607 | 6 | 26 | 406 | 66 |
| Drug ineffective | 586 | 7 | 45 | 142 | 1 |
| Anaemia | 575 | 6 | 36 | 195 | 25 |
| Live birth | 544 | 6 | 0 | 133 | 12 |
| Low birth weight baby | 513 | 5 | 16 | 19 | 6 |
| Fatigue | 477 | 5 | 25 | 113 | 6 |
| Pneumonia | 466 | 6 | 47 | 362 | 12 |
| Immune reconstitution inflammatory syndrome | 445 | 6 | 58 | 245 | 26 |
| Renal impairment | 438 | 6 | 19 | 159 | 21 |
| Rash | 420 | 6 | 15 | 132 | 37 |