Bispecific CD20-directed CD3 T Cell Engager [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Cytokine release syndrome | 966 | 2 | 168 | 746 | 73 |
| Off label use | 358 | 2 | 106 | 226 | 32 |
| Pyrexia | 336 | 2 | 66 | 280 | 44 |
| Febrile neutropenia | 288 | 2 | 21 | 271 | 61 |
| Disease progression | 262 | 2 | 120 | 75 | 15 |
| Pneumonia | 195 | 2 | 49 | 158 | 25 |
| Neutropenia | 193 | 2 | 42 | 125 | 41 |
| Covid-19 | 187 | 2 | 36 | 139 | 7 |
| Death | 185 | 2 | 185 | 30 | 3 |
| Sepsis | 135 | 2 | 61 | 109 | 29 |
| Immune effector cell-associated neurotoxicity syndrome | 123 | 2 | 51 | 63 | 15 |
| Hypotension | 112 | 2 | 32 | 92 | 25 |
| Diffuse large b-cell lymphoma | 107 | 2 | 54 | 15 | 0 |
| Diarrhoea | 97 | 2 | 11 | 89 | 5 |
| Thrombocytopenia | 92 | 2 | 28 | 67 | 33 |
| Septic shock | 92 | 2 | 80 | 57 | 32 |
| Acute kidney injury | 83 | 2 | 17 | 77 | 4 |
| C-reactive protein increased | 80 | 2 | 2 | 78 | 3 |
| Anaemia | 72 | 2 | 28 | 52 | 22 |
| Infection | 67 | 2 | 38 | 29 | 4 |
| Covid-19 pneumonia | 66 | 2 | 28 | 58 | 2 |
| Dyspnoea | 61 | 2 | 15 | 55 | 10 |
| Drug ineffective | 61 | 2 | 14 | 12 | 0 |
| Abdominal pain | 59 | 2 | 11 | 48 | 1 |
| Respiratory failure | 58 | 2 | 31 | 37 | 32 |
| Product use issue | 57 | 2 | 18 | 39 | 9 |
| Fatigue | 57 | 2 | 8 | 45 | 12 |
| Hypoxia | 52 | 2 | 8 | 45 | 12 |
| Constipation | 52 | 1 | 2 | 50 | 4 |
| Asthenia | 48 | 2 | 13 | 39 | 10 |