Central Nervous System Depression [PE] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Nausea | 5,115 | 3 | 25 | 628 | 107 |
| Somnolence | 4,962 | 3 | 35 | 886 | 157 |
| Drug ineffective | 4,917 | 3 | 16 | 468 | 43 |
| Anxiety | 4,355 | 3 | 38 | 775 | 132 |
| Insomnia | 4,065 | 3 | 27 | 432 | 41 |
| Fatigue | 3,470 | 3 | 17 | 433 | 111 |
| Feeling abnormal | 3,453 | 3 | 7 | 275 | 19 |
| Headache | 3,437 | 3 | 8 | 414 | 97 |
| Depression | 3,338 | 2 | 42 | 611 | 51 |
| Dizziness | 3,266 | 3 | 24 | 396 | 35 |
| Fall | 3,139 | 3 | 57 | 1,194 | 114 |
| Condition aggravated | 2,803 | 2 | 19 | 464 | 29 |
| Weight decreased | 2,773 | 2 | 18 | 327 | 23 |
| Vomiting | 2,622 | 2 | 36 | 573 | 140 |
| Drug abuse | 2,612 | 2 | 437 | 1,116 | 203 |
| Sleep apnoea syndrome | 2,526 | 2 | 9 | 150 | 1 |
| Unevaluable event | 2,441 | 2 | 12 | 163 | 17 |
| Toxicity to various agents | 2,292 | 3 | 1,325 | 938 | 417 |
| Pre-existing condition improved | 2,232 | 2 | 1 | 189 | 2 |
| Hypertension | 2,225 | 2 | 26 | 415 | 42 |
| Off label use | 2,120 | 2 | 44 | 487 | 49 |
| Malaise | 2,017 | 3 | 12 | 345 | 101 |
| Completed suicide | 1,950 | 3 | 1,939 | 468 | 16 |
| Pain | 1,934 | 3 | 31 | 445 | 99 |
| Intentional product use issue | 1,836 | 2 | 17 | 207 | 7 |
| Suicidal ideation | 1,822 | 2 | 12 | 539 | 68 |
| Therapeutic response unexpected | 1,758 | 2 | 0 | 99 | 0 |
| Suicide attempt | 1,758 | 3 | 28 | 976 | 373 |
| Blood pressure increased | 1,738 | 3 | 3 | 327 | 85 |
| Wrong technique in product usage process | 1,676 | 2 | 3 | 116 | 3 |