Colony Stimulating Factor Receptor Type 1 (CSF-1R) Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Fatigue | 435 | 2 | 3 | 38 | 0 |
| Product dose omission issue | 347 | 2 | 3 | 31 | 0 |
| Hair colour changes | 327 | 1 | 1 | 27 | 0 |
| Nausea | 233 | 2 | 2 | 25 | 0 |
| Pruritus | 209 | 2 | 0 | 10 | 0 |
| Rash | 146 | 2 | 2 | 12 | 0 |
| Aspartate aminotransferase increased | 140 | 2 | 3 | 21 | 0 |
| Off label use | 130 | 1 | 6 | 16 | 0 |
| Alanine aminotransferase increased | 124 | 1 | 1 | 20 | 0 |
| Headache | 120 | 2 | 0 | 12 | 0 |
| Diarrhoea | 112 | 2 | 3 | 12 | 0 |
| Pain | 111 | 2 | 1 | 15 | 0 |
| Arthralgia | 107 | 2 | 0 | 13 | 0 |
| Periorbital swelling | 95 | 2 | 0 | 5 | 0 |
| Therapy cessation | 94 | 1 | 2 | 6 | 0 |
| Product dose omission in error | 86 | 1 | 0 | 7 | 0 |
| Hepatic enzyme increased | 81 | 2 | 0 | 11 | 0 |
| Dizziness | 79 | 1 | 0 | 11 | 0 |
| Gamma-glutamyltransferase increased | 78 | 1 | 1 | 10 | 0 |
| Decreased appetite | 78 | 1 | 0 | 12 | 0 |
| Swelling face | 76 | 2 | 0 | 4 | 0 |
| Blood alkaline phosphatase increased | 75 | 1 | 1 | 13 | 0 |
| Product use issue | 71 | 2 | 1 | 7 | 0 |
| Feeling abnormal | 70 | 1 | 1 | 8 | 0 |
| Constipation | 68 | 1 | 0 | 8 | 0 |
| Vomiting | 67 | 1 | 0 | 9 | 0 |
| Eye swelling | 67 | 2 | 0 | 5 | 0 |
| Abdominal discomfort | 66 | 1 | 1 | 11 | 0 |
| Peripheral swelling | 59 | 2 | 0 | 2 | 0 |
| Asthenia | 59 | 2 | 4 | 8 | 0 |