Echinocandin Antifungal [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 1,902 | 3 | 1,085 | 890 | 252 |
| Off label use | 995 | 4 | 292 | 320 | 80 |
| Product use in unapproved indication | 469 | 3 | 112 | 185 | 15 |
| Multiple organ dysfunction syndrome | 452 | 3 | 411 | 243 | 74 |
| Death | 315 | 3 | 315 | 52 | 4 |
| Septic shock | 301 | 3 | 230 | 178 | 59 |
| Drug resistance | 298 | 3 | 165 | 99 | 29 |
| Candida infection | 289 | 3 | 143 | 150 | 24 |
| Pyrexia | 276 | 3 | 89 | 172 | 36 |
| Pneumonia | 254 | 3 | 180 | 97 | 24 |
| Fungal infection | 250 | 3 | 134 | 142 | 23 |
| Neutropenia | 238 | 3 | 124 | 106 | 36 |
| Condition aggravated | 237 | 3 | 129 | 102 | 40 |
| Sepsis | 235 | 3 | 167 | 119 | 47 |
| Acute kidney injury | 227 | 3 | 93 | 148 | 50 |
| Aspergillus infection | 221 | 2 | 123 | 103 | 25 |
| Respiratory failure | 218 | 3 | 149 | 131 | 58 |
| Renal failure | 206 | 3 | 120 | 105 | 55 |
| Diarrhoea | 193 | 3 | 89 | 98 | 37 |
| Bronchopulmonary aspergillosis | 182 | 3 | 107 | 118 | 28 |
| Product use issue | 177 | 3 | 37 | 22 | 5 |
| Febrile neutropenia | 164 | 3 | 56 | 105 | 28 |
| Drug reaction with eosinophilia and systemic symptoms | 160 | 3 | 13 | 116 | 28 |
| Systemic mycosis | 156 | 2 | 88 | 43 | 9 |
| Pathogen resistance | 155 | 3 | 48 | 55 | 4 |
| Drug ineffective for unapproved indication | 149 | 3 | 95 | 78 | 23 |
| Pancytopenia | 146 | 3 | 54 | 90 | 14 |
| Toxic epidermal necrolysis | 141 | 3 | 70 | 58 | 38 |
| Systemic candida | 140 | 3 | 51 | 76 | 15 |
| Infection | 128 | 3 | 56 | 87 | 25 |