Increased Large Intestinal Motility [PE] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 7,564 | 8 | 1,430 | 3,921 | 1,474 |
| Nausea | 7,039 | 7 | 1,255 | 2,692 | 989 |
| Paraesthesia | 6,501 | 6 | 473 | 485 | 409 |
| Off label use | 4,796 | 9 | 1,475 | 3,273 | 1,436 |
| Dizziness | 4,607 | 6 | 488 | 879 | 463 |
| Pain | 3,990 | 7 | 651 | 2,954 | 837 |
| Dyspnoea | 3,302 | 7 | 1,047 | 2,241 | 1,313 |
| Constipation | 3,291 | 7 | 833 | 2,571 | 594 |
| Abdominal pain | 3,194 | 7 | 1,022 | 1,960 | 716 |
| Feeling hot | 3,133 | 3 | 110 | 165 | 132 |
| Vomiting | 3,124 | 7 | 1,338 | 1,725 | 1,065 |
| Hyperhidrosis | 2,848 | 5 | 15 | 164 | 55 |
| Asthenia | 2,848 | 6 | 595 | 1,012 | 589 |
| Pallor | 2,787 | 4 | 3 | 62 | 12 |
| Headache | 2,692 | 6 | 477 | 1,923 | 543 |
| Pyrexia | 2,628 | 6 | 442 | 2,135 | 434 |
| Malaise | 2,597 | 6 | 425 | 1,868 | 461 |
| Hypotension | 2,425 | 7 | 265 | 1,720 | 427 |
| Diarrhoea | 2,385 | 6 | 584 | 1,102 | 562 |
| Condition aggravated | 2,371 | 8 | 1,346 | 1,706 | 1,283 |
| Macular degeneration | 2,350 | 6 | 0 | 1,055 | 2 |
| Product use in unapproved indication | 2,201 | 8 | 935 | 1,300 | 975 |
| Dyspepsia | 2,191 | 6 | 320 | 1,286 | 326 |
| Therapeutic product effect incomplete | 1,992 | 6 | 353 | 1,749 | 459 |
| Maternal exposure during pregnancy | 1,948 | 6 | 574 | 919 | 582 |
| Fatigue | 1,903 | 6 | 495 | 1,084 | 538 |
| Anaemia | 1,876 | 7 | 585 | 1,643 | 551 |
| Drug hypersensitivity | 1,815 | 8 | 997 | 1,164 | 926 |
| Infusion related reaction | 1,808 | 6 | 544 | 1,596 | 503 |
| Hypertension | 1,775 | 7 | 786 | 1,377 | 759 |