Tetracycline-class Antibacterial [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Off label use | 855 | 3 | 156 | 279 | 44 |
| Drug ineffective | 583 | 3 | 280 | 243 | 74 |
| Nausea | 465 | 3 | 24 | 125 | 6 |
| Vomiting | 295 | 2 | 6 | 88 | 16 |
| Diarrhoea | 204 | 3 | 17 | 71 | 15 |
| Coagulopathy | 173 | 1 | 7 | 59 | 15 |
| Thrombocytopenia | 172 | 3 | 66 | 113 | 36 |
| Death | 172 | 2 | 171 | 25 | 1 |
| Drug resistance | 168 | 2 | 47 | 55 | 6 |
| Condition aggravated | 149 | 2 | 35 | 62 | 16 |
| Pathogen resistance | 132 | 2 | 66 | 47 | 23 |
| Sepsis | 128 | 2 | 69 | 57 | 15 |
| Septic shock | 120 | 1 | 93 | 65 | 28 |
| Treatment failure | 119 | 2 | 64 | 57 | 4 |
| Platelet count decreased | 113 | 2 | 7 | 47 | 22 |
| Rash | 108 | 2 | 3 | 32 | 2 |
| Acute kidney injury | 108 | 2 | 37 | 53 | 12 |
| Pancreatitis acute | 107 | 2 | 27 | 69 | 6 |
| Drug ineffective for unapproved indication | 99 | 2 | 43 | 44 | 8 |
| Hepatic function abnormal | 98 | 2 | 6 | 37 | 7 |
| Product use in unapproved indication | 97 | 2 | 23 | 31 | 2 |
| Blood fibrinogen decreased | 90 | 2 | 11 | 28 | 11 |
| Hypofibrinogenaemia | 88 | 1 | 11 | 20 | 15 |
| Fatigue | 88 | 2 | 21 | 39 | 4 |
| Pyrexia | 87 | 2 | 16 | 55 | 15 |
| Blood bilirubin increased | 84 | 3 | 3 | 26 | 3 |
| Renal impairment | 81 | 2 | 15 | 41 | 10 |
| Decreased appetite | 80 | 2 | 7 | 31 | 2 |
| Multiple organ dysfunction syndrome | 72 | 2 | 70 | 32 | 16 |
| Liver injury | 68 | 1 | 2 | 14 | 1 |