Androgen Receptor Antagonists [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Fatigue | 9,172 | 5 | 617 | 1,194 | 54 |
| Death | 6,855 | 3 | 6,852 | 727 | 43 |
| Malignant neoplasm progression | 5,054 | 3 | 1,535 | 739 | 36 |
| Prostatic specific antigen increased | 4,092 | 4 | 340 | 513 | 25 |
| Drug ineffective | 3,857 | 4 | 283 | 313 | 18 |
| Asthenia | 3,835 | 4 | 392 | 843 | 25 |
| Hot flush | 3,370 | 3 | 129 | 283 | 5 |
| Decreased appetite | 3,193 | 3 | 435 | 859 | 22 |
| Nausea | 3,037 | 4 | 270 | 604 | 30 |
| Dizziness | 2,893 | 3 | 203 | 539 | 13 |
| Diarrhoea | 2,564 | 3 | 219 | 523 | 21 |
| Back pain | 2,076 | 3 | 193 | 373 | 10 |
| Underdose | 2,022 | 2 | 394 | 321 | 13 |
| Arthralgia | 1,912 | 3 | 119 | 251 | 2 |
| Constipation | 1,715 | 2 | 155 | 334 | 5 |
| Fall | 1,682 | 2 | 235 | 800 | 25 |
| Weight decreased | 1,654 | 2 | 159 | 346 | 10 |
| Pain | 1,547 | 4 | 175 | 393 | 6 |
| Headache | 1,545 | 2 | 71 | 220 | 10 |
| Malaise | 1,445 | 2 | 234 | 513 | 23 |
| Dyspnoea | 1,431 | 3 | 175 | 473 | 41 |
| Peripheral swelling | 1,301 | 2 | 136 | 214 | 0 |
| Insomnia | 1,270 | 3 | 72 | 151 | 1 |
| Dysphagia | 1,180 | 2 | 166 | 260 | 11 |
| Vomiting | 1,152 | 3 | 149 | 420 | 14 |
| Pain in extremity | 1,117 | 4 | 93 | 215 | 3 |
| Off label use | 1,066 | 4 | 165 | 213 | 24 |
| Somnolence | 944 | 3 | 85 | 169 | 6 |
| Muscular weakness | 927 | 2 | 81 | 255 | 12 |
| Abdominal discomfort | 918 | 2 | 60 | 134 | 3 |