HIV Integrase Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Foetal exposure during pregnancy | 2,099 | 3 | 236 | 191 | 45 |
| Off label use | 1,650 | 3 | 179 | 131 | 9 |
| Exposure during pregnancy | 1,632 | 3 | 133 | 189 | 15 |
| Virologic failure | 1,562 | 3 | 29 | 113 | 4 |
| Product dose omission issue | 1,475 | 3 | 1 | 58 | 0 |
| Pathogen resistance | 1,281 | 3 | 4 | 55 | 5 |
| Maternal exposure during pregnancy | 1,251 | 3 | 35 | 112 | 13 |
| Viral mutation identified | 963 | 3 | 6 | 25 | 1 |
| Injection site pain | 924 | 1 | 3 | 25 | 1 |
| Death | 887 | 3 | 881 | 75 | 26 |
| Treatment failure | 834 | 3 | 201 | 26 | 8 |
| Depression | 795 | 3 | 112 | 170 | 8 |
| Pyrexia | 782 | 3 | 134 | 246 | 29 |
| Drug ineffective | 775 | 3 | 143 | 102 | 8 |
| Drug interaction | 755 | 3 | 112 | 195 | 17 |
| Blood hiv rna increased | 754 | 3 | 21 | 46 | 8 |
| Fatigue | 736 | 3 | 117 | 108 | 14 |
| Pain | 693 | 3 | 106 | 44 | 10 |
| Headache | 690 | 3 | 107 | 119 | 13 |
| Drug resistance | 663 | 3 | 106 | 96 | 2 |
| Treatment noncompliance | 662 | 3 | 25 | 140 | 6 |
| Nausea | 630 | 3 | 34 | 154 | 23 |
| Rash | 624 | 3 | 111 | 119 | 25 |
| Viral load increased | 622 | 3 | 11 | 49 | 2 |
| Abortion spontaneous | 615 | 3 | 36 | 50 | 5 |
| Immune reconstitution inflammatory syndrome | 577 | 2 | 77 | 294 | 34 |
| Diarrhoea | 544 | 3 | 29 | 161 | 22 |
| Premature baby | 449 | 3 | 43 | 67 | 32 |
| Condition aggravated | 423 | 3 | 55 | 148 | 15 |
| No adverse event | 418 | 3 | 1 | 2 | 0 |