Cyclooxygenase Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 64,474 | 20 | 4,104 | 10,951 | 5,247 |
| Off label use | 29,056 | 20 | 5,837 | 11,392 | 6,542 |
| Drug hypersensitivity | 26,616 | 21 | 3,964 | 6,973 | 4,663 |
| Pain | 24,346 | 20 | 4,881 | 9,211 | 5,603 |
| Product use in unapproved indication | 23,044 | 18 | 3,349 | 5,023 | 3,872 |
| Fatigue | 21,580 | 19 | 5,639 | 9,511 | 5,996 |
| Nausea | 21,088 | 22 | 4,320 | 10,459 | 4,992 |
| Rash | 19,146 | 20 | 5,282 | 8,069 | 5,718 |
| Vomiting | 18,769 | 17 | 5,399 | 11,151 | 5,870 |
| Product use issue | 18,215 | 16 | 2,799 | 4,572 | 3,092 |
| Arthralgia | 18,064 | 18 | 5,104 | 7,793 | 5,242 |
| Dyspnoea | 17,483 | 19 | 4,492 | 9,073 | 4,847 |
| Headache | 17,268 | 20 | 4,910 | 8,496 | 4,852 |
| Abdominal discomfort | 16,999 | 18 | 4,611 | 7,424 | 5,280 |
| Gastrointestinal haemorrhage | 16,985 | 17 | 3,092 | 13,738 | 910 |
| Rheumatoid arthritis | 16,842 | 15 | 5,339 | 7,049 | 5,795 |
| Dizziness | 15,865 | 20 | 4,464 | 8,252 | 4,524 |
| Diarrhoea | 15,396 | 17 | 4,999 | 8,052 | 5,062 |
| Condition aggravated | 15,080 | 19 | 4,561 | 8,172 | 5,234 |
| Hypersensitivity | 14,408 | 20 | 4,484 | 6,312 | 4,932 |
| Drug intolerance | 13,787 | 16 | 3,794 | 5,967 | 4,471 |
| Joint swelling | 13,734 | 15 | 5,094 | 6,327 | 5,555 |
| Abdominal pain upper | 13,267 | 20 | 4,273 | 7,063 | 4,577 |
| Malaise | 13,182 | 16 | 4,432 | 6,789 | 4,465 |
| Pruritus | 12,966 | 20 | 3,852 | 5,546 | 3,728 |
| Swelling | 12,231 | 15 | 4,852 | 6,265 | 5,411 |
| Contraindicated product administered | 12,137 | 14 | 3,373 | 5,348 | 3,866 |
| Urticaria | 12,091 | 21 | 4,490 | 5,349 | 4,872 |
| Arthropathy | 11,917 | 12 | 4,297 | 6,688 | 4,883 |
| Alopecia | 11,782 | 14 | 4,493 | 5,881 | 5,250 |