Cytochrome P450 2C9 Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 9,571 | 13 | 2,867 | 4,026 | 1,448 |
| Off label use | 9,549 | 14 | 1,779 | 3,650 | 774 |
| Fatigue | 6,065 | 13 | 650 | 1,596 | 349 |
| Seizure | 5,374 | 12 | 138 | 1,757 | 66 |
| Diarrhoea | 5,363 | 13 | 549 | 1,480 | 194 |
| Drug interaction | 4,939 | 10 | 504 | 2,272 | 539 |
| Nausea | 4,607 | 14 | 623 | 1,598 | 284 |
| Death | 4,529 | 12 | 4,514 | 774 | 155 |
| Dyspnoea | 4,051 | 15 | 791 | 2,229 | 599 |
| Product use in unapproved indication | 3,666 | 10 | 570 | 1,158 | 312 |
| Asthenia | 3,569 | 14 | 658 | 1,583 | 396 |
| Hospitalisation | 3,482 | 11 | 116 | 3,460 | 10 |
| Vomiting | 3,263 | 14 | 563 | 1,436 | 269 |
| Pyrexia | 3,052 | 14 | 570 | 1,789 | 269 |
| Condition aggravated | 2,920 | 13 | 727 | 1,292 | 402 |
| Decreased appetite | 2,788 | 11 | 347 | 1,032 | 138 |
| Rash | 2,759 | 15 | 251 | 735 | 128 |
| Headache | 2,719 | 14 | 280 | 773 | 108 |
| Weight decreased | 2,652 | 13 | 249 | 1,020 | 131 |
| Dizziness | 2,543 | 14 | 139 | 848 | 159 |
| Pneumonia | 2,429 | 12 | 784 | 1,738 | 314 |
| Malaise | 2,123 | 15 | 222 | 1,037 | 122 |
| Cough | 2,067 | 12 | 349 | 856 | 268 |
| Pain | 2,064 | 15 | 265 | 667 | 74 |
| Anaemia | 1,957 | 9 | 489 | 1,167 | 321 |
| Constipation | 1,941 | 11 | 477 | 748 | 155 |
| Acute kidney injury | 1,936 | 12 | 358 | 1,360 | 348 |
| Somnolence | 1,843 | 10 | 256 | 576 | 160 |
| Abdominal pain | 1,802 | 13 | 446 | 910 | 203 |
| Drug resistance | 1,762 | 9 | 436 | 345 | 80 |