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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Cytochrome P450 3A4 Inhibitors [MoA] — Common Side Effects

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Side Effect Total Reports Drugs Deaths Hosp. Life-Threat.
Drug ineffective 33,154 33 5,212 9,058 2,600
Death 27,867 32 27,778 2,058 301
Diarrhoea 24,873 35 2,590 6,718 1,248
Off label use 23,584 34 3,434 7,651 1,880
Nausea 19,830 35 1,936 6,167 934
Fatigue 18,490 34 2,238 5,258 1,058
Dyspnoea 15,396 34 2,756 7,187 1,615
Headache 13,565 33 1,707 3,804 836
Vomiting 12,539 35 2,085 5,063 1,136
Pyrexia 11,727 34 2,682 6,932 1,490
Rash 11,685 35 1,175 3,537 980
Sickle cell anaemia with crisis 11,023 1 38 6,090 27
Product use in unapproved indication 10,860 26 1,930 2,878 1,005
Pain 10,491 34 1,154 4,547 1,017
Malaise 10,377 32 1,701 4,060 893
Drug interaction 9,990 32 1,220 4,259 980
Dizziness 8,500 34 1,503 2,871 834
Pneumonia 8,491 30 2,473 5,254 1,215
Weight decreased 8,324 31 1,010 3,316 656
Pruritus 8,231 33 1,442 2,480 873
Asthenia 8,176 33 1,816 3,604 856
Product dose omission issue 8,053 29 72 3,109 52
Malignant neoplasm progression 7,843 17 2,725 1,891 290
Decreased appetite 7,817 34 1,825 3,019 825
Condition aggravated 7,748 32 1,697 3,579 1,349
Drug intolerance 7,365 27 873 1,807 687
Arthralgia 7,276 31 1,296 2,558 685
Hypertension 7,004 27 1,149 2,811 896
Cough 6,671 28 1,102 2,518 349
Abdominal pain 6,580 33 1,319 2,915 559
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