Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Bone density decreased | 10,727 | 5 | 159 | 660 | 1 |
| Renal injury | 9,371 | 5 | 168 | 526 | 0 |
| Skeletal injury | 8,320 | 1 | 172 | 490 | 0 |
| Chronic kidney disease | 7,417 | 5 | 220 | 918 | 5 |
| Osteonecrosis | 7,293 | 5 | 107 | 470 | 0 |
| Bone loss | 7,052 | 3 | 107 | 382 | 0 |
| Multiple fractures | 6,883 | 4 | 110 | 450 | 1 |
| Renal failure | 6,748 | 5 | 347 | 1,014 | 21 |
| Osteoporosis | 5,746 | 5 | 80 | 581 | 3 |
| Tooth loss | 4,483 | 1 | 57 | 266 | 0 |
| Drug resistance | 3,404 | 5 | 119 | 520 | 14 |
| Pain | 3,284 | 5 | 161 | 561 | 4 |
| Foetal exposure during pregnancy | 3,017 | 5 | 388 | 335 | 26 |
| Virologic failure | 2,858 | 5 | 101 | 147 | 16 |
| Emotional distress | 2,849 | 2 | 71 | 375 | 0 |
| Pathogen resistance | 2,839 | 5 | 41 | 157 | 6 |
| Anxiety | 2,774 | 5 | 79 | 537 | 2 |
| Viral mutation identified | 2,639 | 5 | 31 | 109 | 0 |
| Anhedonia | 2,449 | 2 | 57 | 331 | 0 |
| Renal impairment | 2,329 | 5 | 60 | 431 | 12 |
| Osteopenia | 2,273 | 3 | 16 | 183 | 0 |
| Drug ineffective | 2,101 | 5 | 293 | 297 | 37 |
| Tooth injury | 2,019 | 3 | 21 | 84 | 0 |
| Blood creatinine increased | 1,900 | 5 | 39 | 338 | 15 |
| Death | 1,473 | 5 | 1,461 | 134 | 38 |
| Acute kidney injury | 1,455 | 4 | 102 | 677 | 51 |
| Treatment failure | 1,390 | 5 | 120 | 48 | 4 |
| Maternal exposure during pregnancy | 1,219 | 4 | 62 | 183 | 14 |
| Exposure during pregnancy | 1,213 | 5 | 104 | 150 | 17 |
| Nephropathy | 1,084 | 4 | 45 | 135 | 0 |