P-Glycoprotein Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 34,173 | 52 | 2,966 | 6,916 | 2,380 |
| Off label use | 28,296 | 51 | 5,492 | 7,962 | 2,033 |
| Death | 24,936 | 48 | 24,858 | 2,344 | 339 |
| Fatigue | 24,660 | 51 | 1,727 | 5,124 | 1,010 |
| Nausea | 20,076 | 52 | 1,764 | 5,743 | 908 |
| Diarrhoea | 18,805 | 53 | 1,827 | 5,140 | 847 |
| Dyspnoea | 14,627 | 48 | 2,208 | 6,567 | 1,445 |
| Headache | 12,933 | 50 | 1,031 | 3,056 | 636 |
| Dizziness | 12,863 | 48 | 1,171 | 3,343 | 798 |
| Asthenia | 11,817 | 50 | 1,895 | 4,529 | 955 |
| Vomiting | 11,355 | 50 | 1,675 | 4,553 | 990 |
| Rash | 10,502 | 52 | 897 | 2,659 | 809 |
| Product use in unapproved indication | 9,942 | 35 | 1,927 | 2,660 | 993 |
| Pain | 9,839 | 50 | 1,021 | 3,172 | 897 |
| Malaise | 9,459 | 47 | 1,145 | 3,612 | 662 |
| Pyrexia | 9,302 | 47 | 1,820 | 5,751 | 822 |
| Arthralgia | 9,236 | 46 | 1,060 | 2,129 | 575 |
| Pneumonia | 8,932 | 47 | 2,760 | 5,678 | 1,213 |
| Hot flush | 8,005 | 29 | 33 | 437 | 22 |
| Weight decreased | 7,812 | 47 | 473 | 2,581 | 305 |
| Pruritus | 7,760 | 47 | 642 | 1,505 | 294 |
| Drug interaction | 7,684 | 43 | 742 | 3,624 | 767 |
| Acute kidney injury | 7,039 | 35 | 1,075 | 5,086 | 986 |
| Condition aggravated | 6,827 | 41 | 1,334 | 2,633 | 1,120 |
| Hypertension | 6,777 | 41 | 866 | 2,459 | 765 |
| Constipation | 6,767 | 47 | 521 | 1,720 | 214 |
| Decreased appetite | 6,734 | 45 | 1,013 | 2,320 | 399 |
| Insomnia | 6,639 | 43 | 777 | 1,404 | 468 |
| Cough | 6,486 | 42 | 954 | 2,151 | 454 |
| Anaemia | 6,467 | 42 | 943 | 3,183 | 576 |