Penicillin-class Antibacterial [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug hypersensitivity | 6,819 | 8 | 57 | 652 | 108 |
| Rash | 3,208 | 8 | 48 | 992 | 239 |
| Drug ineffective | 3,000 | 8 | 362 | 1,178 | 293 |
| Pruritus | 2,421 | 8 | 31 | 929 | 150 |
| Dyspnoea | 2,244 | 7 | 268 | 992 | 437 |
| Urticaria | 2,154 | 8 | 4 | 548 | 112 |
| Diarrhoea | 2,054 | 8 | 179 | 851 | 182 |
| Hypersensitivity | 2,053 | 7 | 16 | 395 | 81 |
| Nausea | 1,813 | 7 | 94 | 872 | 111 |
| Off label use | 1,777 | 8 | 173 | 907 | 162 |
| Acute kidney injury | 1,688 | 8 | 181 | 1,242 | 256 |
| Malaise | 1,601 | 7 | 95 | 768 | 183 |
| Pyrexia | 1,586 | 8 | 140 | 1,091 | 233 |
| Vomiting | 1,585 | 7 | 149 | 760 | 199 |
| Erythema | 1,477 | 7 | 26 | 725 | 106 |
| Headache | 1,363 | 6 | 56 | 556 | 40 |
| Drug reaction with eosinophilia and systemic symptoms | 1,186 | 7 | 54 | 751 | 152 |
| Maternal exposure during pregnancy | 1,149 | 7 | 31 | 198 | 46 |
| Pain | 1,122 | 6 | 23 | 467 | 46 |
| Anaphylactic reaction | 1,122 | 5 | 16 | 401 | 222 |
| Condition aggravated | 1,048 | 7 | 246 | 666 | 304 |
| Abdominal pain | 1,041 | 5 | 51 | 551 | 61 |
| Rash maculo-papular | 1,028 | 6 | 42 | 558 | 51 |
| Angioedema | 1,025 | 4 | 5 | 216 | 80 |
| Fatigue | 1,012 | 7 | 38 | 403 | 58 |
| Foetal exposure during pregnancy | 1,003 | 6 | 122 | 239 | 49 |
| Dizziness | 885 | 7 | 24 | 298 | 55 |
| Anaphylactic shock | 862 | 5 | 27 | 420 | 349 |
| Macular degeneration | 756 | 1 | 0 | 225 | 1 |
| Product use in unapproved indication | 755 | 7 | 69 | 262 | 54 |