Polymyxin-class Antibacterial [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 308 | 2 | 58 | 105 | 26 |
| Off label use | 181 | 2 | 20 | 69 | 10 |
| Macular degeneration | 168 | 1 | 0 | 44 | 0 |
| Acute kidney injury | 144 | 2 | 18 | 68 | 18 |
| Condition aggravated | 88 | 2 | 14 | 29 | 2 |
| Drug hypersensitivity | 72 | 2 | 2 | 6 | 0 |
| Nausea | 69 | 2 | 1 | 42 | 0 |
| Pain | 66 | 1 | 0 | 37 | 0 |
| Malaise | 57 | 2 | 2 | 49 | 2 |
| Death | 55 | 2 | 54 | 5 | 3 |
| Drug resistance | 53 | 2 | 25 | 27 | 5 |
| Septic shock | 52 | 2 | 38 | 24 | 22 |
| Pyrexia | 52 | 2 | 3 | 47 | 5 |
| Anaemia | 48 | 2 | 6 | 46 | 9 |
| Multiple organ dysfunction syndrome | 46 | 2 | 36 | 27 | 19 |
| Erythema | 45 | 2 | 0 | 34 | 0 |
| Paraesthesia oral | 42 | 1 | 0 | 39 | 0 |
| Pathogen resistance | 41 | 2 | 20 | 15 | 14 |
| Eosinophilia | 41 | 2 | 0 | 10 | 2 |
| Weight decreased | 40 | 1 | 0 | 40 | 0 |
| Infusion related reaction | 40 | 1 | 1 | 38 | 2 |
| Headache | 40 | 2 | 1 | 35 | 1 |
| Therapeutic product effect incomplete | 39 | 1 | 0 | 39 | 0 |
| Dyspepsia | 38 | 1 | 0 | 38 | 0 |
| Chronic sinusitis | 38 | 1 | 0 | 38 | 0 |
| Rash maculo-papular | 37 | 1 | 0 | 3 | 1 |
| Procedural pain | 37 | 1 | 0 | 37 | 0 |
| Pneumonia | 35 | 2 | 8 | 17 | 5 |
| Thrombocytopenia | 34 | 1 | 1 | 3 | 1 |
| Renal failure | 34 | 2 | 8 | 18 | 1 |