Tetracycline-class Drug [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 4,955 | 4 | 1,368 | 2,045 | 1,316 |
| Drug hypersensitivity | 4,205 | 3 | 1,059 | 1,430 | 1,121 |
| Off label use | 3,928 | 3 | 1,610 | 2,165 | 1,542 |
| Nausea | 3,174 | 3 | 1,055 | 1,491 | 1,034 |
| Rash | 2,908 | 4 | 1,286 | 1,597 | 1,216 |
| Vomiting | 2,726 | 3 | 1,163 | 1,473 | 1,084 |
| Condition aggravated | 2,516 | 3 | 1,239 | 1,549 | 1,132 |
| Headache | 2,465 | 4 | 1,060 | 1,304 | 1,045 |
| Fatigue | 2,430 | 3 | 1,268 | 1,560 | 1,222 |
| Pain | 2,413 | 3 | 1,192 | 1,504 | 1,197 |
| Rheumatoid arthritis | 2,408 | 3 | 1,342 | 1,442 | 1,238 |
| Drug intolerance | 2,335 | 3 | 1,054 | 1,370 | 1,135 |
| Arthralgia | 2,240 | 3 | 1,128 | 1,351 | 1,096 |
| Malaise | 2,069 | 3 | 1,049 | 1,268 | 1,053 |
| Diarrhoea | 2,026 | 3 | 987 | 1,140 | 937 |
| Abdominal discomfort | 2,023 | 3 | 1,192 | 1,300 | 1,135 |
| Dizziness | 2,007 | 4 | 1,085 | 1,077 | 971 |
| Joint swelling | 2,003 | 3 | 1,272 | 1,392 | 1,237 |
| Dyspnoea | 1,970 | 3 | 890 | 1,356 | 918 |
| Product use in unapproved indication | 1,887 | 3 | 948 | 1,086 | 879 |
| Hypersensitivity | 1,877 | 3 | 1,153 | 1,237 | 1,080 |
| General physical health deterioration | 1,829 | 3 | 1,342 | 1,313 | 1,155 |
| Hypertension | 1,816 | 3 | 1,300 | 1,399 | 1,172 |
| Hepatic enzyme increased | 1,796 | 3 | 1,311 | 1,348 | 1,173 |
| Treatment failure | 1,769 | 3 | 826 | 914 | 798 |
| Hypoaesthesia | 1,766 | 3 | 1,340 | 1,229 | 1,163 |
| Pneumonia | 1,738 | 3 | 1,070 | 1,219 | 932 |
| Urticaria | 1,734 | 3 | 1,126 | 1,073 | 1,013 |
| Pruritus | 1,725 | 3 | 801 | 1,005 | 774 |
| Synovitis | 1,724 | 3 | 1,246 | 1,242 | 1,142 |