Interleukin 6 Receptor Antagonists [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 37,407 | 2 | 2,474 | 7,384 | 3,311 |
| Rheumatoid arthritis | 24,615 | 2 | 3,019 | 6,452 | 3,546 |
| Pain | 23,217 | 2 | 2,744 | 6,023 | 3,456 |
| Off label use | 20,291 | 2 | 4,171 | 6,777 | 3,779 |
| Arthralgia | 19,675 | 2 | 2,863 | 5,908 | 3,073 |
| Joint swelling | 18,782 | 2 | 2,919 | 5,107 | 3,577 |
| Fatigue | 16,802 | 2 | 3,038 | 5,392 | 3,321 |
| Rash | 15,239 | 2 | 2,826 | 5,088 | 3,256 |
| Drug intolerance | 14,150 | 2 | 2,242 | 4,144 | 2,739 |
| Contraindicated product administered | 13,387 | 2 | 2,009 | 3,747 | 2,449 |
| Alopecia | 12,340 | 2 | 2,600 | 3,920 | 3,223 |
| Abdominal discomfort | 12,153 | 2 | 2,636 | 4,038 | 3,204 |
| Arthropathy | 12,108 | 2 | 2,623 | 4,943 | 3,278 |
| Synovitis | 11,791 | 2 | 2,691 | 4,579 | 3,190 |
| Swelling | 11,771 | 2 | 2,653 | 3,916 | 3,134 |
| Condition aggravated | 11,718 | 2 | 2,440 | 4,400 | 2,868 |
| Hypersensitivity | 11,360 | 2 | 2,492 | 4,310 | 3,004 |
| Systemic lupus erythematosus | 11,160 | 2 | 2,907 | 3,696 | 3,332 |
| Treatment failure | 10,816 | 2 | 1,785 | 2,905 | 2,097 |
| Infusion related reaction | 10,657 | 2 | 2,914 | 4,565 | 3,062 |
| Pemphigus | 10,655 | 2 | 2,654 | 3,396 | 3,254 |
| Hepatic enzyme increased | 10,286 | 2 | 2,887 | 3,894 | 3,203 |
| Headache | 10,281 | 2 | 2,633 | 3,903 | 2,538 |
| Glossodynia | 9,950 | 2 | 2,820 | 3,420 | 3,157 |
| Peripheral swelling | 9,471 | 2 | 2,145 | 4,053 | 2,275 |
| Hand deformity | 9,434 | 2 | 2,808 | 3,515 | 3,180 |
| Drug hypersensitivity | 9,271 | 2 | 2,298 | 4,144 | 2,537 |
| Nausea | 8,915 | 2 | 2,059 | 3,851 | 2,525 |
| Infection | 8,674 | 2 | 1,966 | 3,632 | 2,018 |
| Wound | 8,607 | 2 | 2,672 | 3,400 | 3,085 |