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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Purine Antimetabolite [EPC] — Common Side Effects

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Side Effect Total Reports Drugs Deaths Hosp. Life-Threat.
Drug ineffective 8,265 2 874 2,201 762
Off label use 5,555 2 1,241 2,181 1,052
Drug intolerance 3,406 2 622 1,037 556
Condition aggravated 2,927 2 922 1,441 881
Rheumatoid arthritis 2,772 2 755 980 659
Fatigue 2,657 2 782 1,120 675
Nausea 2,532 2 742 1,220 631
Arthralgia 2,529 2 836 1,159 682
Treatment failure 2,510 2 505 842 439
Pneumonia 2,475 2 1,016 1,200 670
Drug hypersensitivity 2,447 2 652 1,037 598
Headache 2,336 2 788 1,129 689
Rash 2,208 2 731 1,002 606
Product use in unapproved indication 2,161 2 640 902 529
Diarrhoea 2,128 2 710 1,039 536
Pain 1,978 2 755 1,022 623
Joint swelling 1,880 2 734 871 642
Pain in extremity 1,806 2 699 809 657
Hypersensitivity 1,728 2 691 943 603
Pyrexia 1,711 2 459 1,084 392
Maternal exposure during pregnancy 1,709 2 650 828 533
Dyspnoea 1,702 2 679 998 697
Vomiting 1,637 2 673 974 543
Malaise 1,604 2 590 920 586
Hepatic enzyme increased 1,565 2 836 868 660
Therapeutic product effect decreased 1,558 1 453 763 418
Alopecia 1,553 2 815 942 665
Hypertension 1,552 2 900 971 697
Synovitis 1,550 1 729 810 617
Contraindicated product administered 1,481 2 548 742 487
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