Competitive Opioid Antagonists [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Dependence | 329 | 2 | 56 | 2 | 1 |
| Drug hypersensitivity | 255 | 2 | 0 | 3 | 0 |
| Overdose | 211 | 2 | 48 | 6 | 0 |
| Drug ineffective | 98 | 2 | 1 | 10 | 5 |
| Death | 62 | 1 | 62 | 0 | 0 |
| Off label use | 47 | 2 | 1 | 7 | 4 |
| Product dose omission issue | 42 | 1 | 0 | 1 | 0 |
| Drug dependence | 41 | 2 | 6 | 8 | 0 |
| Nausea | 34 | 2 | 1 | 6 | 1 |
| Foetal exposure during pregnancy | 31 | 2 | 1 | 6 | 1 |
| Pain | 30 | 2 | 1 | 2 | 0 |
| Anxiety | 29 | 2 | 2 | 2 | 0 |
| Withdrawal syndrome | 28 | 1 | 4 | 1 | 0 |
| Product quality issue | 28 | 1 | 0 | 0 | 0 |
| Somnolence | 27 | 2 | 1 | 8 | 0 |
| Vomiting | 26 | 2 | 1 | 6 | 1 |
| Depression | 25 | 1 | 4 | 0 | 0 |
| Ill-defined disorder | 22 | 1 | 3 | 0 | 0 |
| Maternal exposure during pregnancy | 20 | 2 | 0 | 2 | 0 |
| Pruritus | 18 | 2 | 0 | 1 | 0 |
| Product dose omission | 17 | 1 | 0 | 0 | 0 |
| Disability | 16 | 2 | 1 | 1 | 0 |
| Feeling abnormal | 15 | 2 | 0 | 3 | 0 |
| Drug withdrawal syndrome neonatal | 15 | 2 | 0 | 5 | 0 |
| Urticaria | 14 | 2 | 0 | 0 | 4 |
| Post-traumatic stress disorder | 14 | 1 | 1 | 2 | 1 |
| Product use issue | 13 | 2 | 0 | 5 | 2 |
| Pancreatitis acute | 13 | 1 | 0 | 12 | 0 |
| Headache | 13 | 2 | 1 | 1 | 0 |
| Product packaging quantity issue | 12 | 1 | 0 | 0 | 0 |